Lineage for d1rtdd_ (1rtd D:)

  1. Root: SCOPe 2.05
  2. 1949014Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)
  3. 1951566Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 1951567Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 1951913Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)
  6. 1951914Protein HIV-1 reverse transcriptase [56689] (3 species)
  7. 1951956Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (153 PDB entries)
    Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
  8. 1952182Domain d1rtdd_: 1rtd D: [43051]
    Other proteins in same PDB: d1rtda1, d1rtdc1
    protein/DNA complex; complexed with mg, ttp

Details for d1rtdd_

PDB Entry: 1rtd (more details), 3.2 Å

PDB Description: structure of a catalytic complex of hiv-1 reverse transcriptase: implications for nucleoside analog drug resistance
PDB Compounds: (D:) protein (reverse transcriptase)

SCOPe Domain Sequences for d1rtdd_:

Sequence, based on SEQRES records: (download)

>d1rtdd_ e.8.1.2 (D:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfa
ikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvplde
dfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyq
ymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvq
pivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaele
laenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgaht
ndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntppl
vklwyql

Sequence, based on observed residues (ATOM records): (download)

>d1rtdd_ e.8.1.2 (D:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfa
ikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvplde
dfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyq
ymddlyvgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvn
diqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvh
gvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqki
ttesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql

SCOPe Domain Coordinates for d1rtdd_:

Click to download the PDB-style file with coordinates for d1rtdd_.
(The format of our PDB-style files is described here.)

Timeline for d1rtdd_: