SCOPe 2.08: Domain d7f5oa1: 7f5o A:1-302

Lineage for d7f5oa1 (7f5o A:1-302)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein automated matches [190252] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187034] (47 PDB entries)

8. Domain d7f5oa1: 7f5o A:1-302 [421875]
   Other proteins in same PDB: d7f5oa2
   automated match to d4y14b_
   complexed with iod

Details for d7f5oa1

PDB Entry: 7f5o, 1.7 Å

PDB Description: crystal structure of ptpn2 catalytic domain

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 2

SCOPe Domain Sequences for d7f5oa1:

Sequence, based on SEQRES records:

>d7f5oa1 c.45.1.2 (A:1-302) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mpttierefeeldtqrrwqplyleirneshdyphrvakfpenrnrnryrdvspydhsrvk
lqnaendyinaslvdieeaqrsyiltqgplpntcchfwlmvwqqktkavvmlnrivekes
vkcaqywptddqemlfketgfsvkllsedvksyytvhllqleninsgetrtishfhyttw
pdfgvpespasflnflfkvresgslnpdhgpavihcsagigrsgtfslvdtclvlmekgd
dinikqvllnmrkyrmgliqtpdqlrfsymaiiegakcikgdssiqkrwkelskedlspa
fd

Sequence, based on observed residues (ATOM records):

>d7f5oa1 c.45.1.2 (A:1-302) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mpttierefeeldtqrrwqplyleirneshdyphrvakfpenrnrnryrdvspydhsrvk
lqnaendyinaslvdieeaqrsyiltqgplpntcchfwlmvwqqktkavvmlnrivekes
vkcaqywptddqemlfketgfsvkllsedvksyytvhllqleninsgetrtishfhyttw
pdfgvpespasflnflfkvresgslnpdhgpavihcsagigrsgtfslvdtclvlminik
qvllnmrkyrmgliqtpdqlrfsymaiiegakiqkrwkelskedlspafd

Timeline for d7f5oa1:

• d7f5oa1 is new in SCOPe 2.08-stable