SCOP 1.67: Domain d1hyhc2: 1hyh C:167-329

Lineage for d1hyhc2 (1hyh C:167-329)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (2 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (4 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)

6. Protein L-2-hydroxyisocapronate dehydrogenase, L-HICDH [56337] (1 species)

7. Species Lactobacillus confusus [TaxId:1583] [56338] (1 PDB entry)

8. Domain d1hyhc2: 1hyh C:167-329 [42119]
   Other proteins in same PDB: d1hyha1, d1hyhb1, d1hyhc1, d1hyhd1

Details for d1hyhc2

PDB Entry: 1hyh, 2.2 Å

PDB Description: crystal structure of l-2-hydroxyisocaproate dehydrogenase from lactobacillus confusus at 2.2 angstroms resolution-an example of strong asymmetry between subunits

SCOP Domain Sequences for d1hyhc2:

Sequence, based on SEQRES records:

>d1hyhc2 d.162.1.1 (C:167-329) L-2-hydroxyisocapronate dehydrogenase, L-HICDH {Lactobacillus confusus}
gtlldtarmqravgeafdldprsvsgynlgehgnsqfvawstvrvmgqpivtladagdid
laaieeearkggftvlngkgytsygvatsairiakavmadahaelvvsnrrddmgmylsy
paiigrdgvlaettldlttdeqekllqsrdyiqqrfdeivdtl

Sequence, based on observed residues (ATOM records):

>d1hyhc2 d.162.1.1 (C:167-329) L-2-hydroxyisocapronate dehydrogenase, L-HICDH {Lactobacillus confusus}
gtlldtarmqravgeafdldprsvsgynlgehgnsqfvawstvrvmgqpivtladaidla
aieeearkggftvlngkgytsygvatsairiakavmadahaelvvsnrrddmgmylsypa
iigrdgvlaettldlttdeqekllqsrdyiqqrfdeivdtl

Timeline for d1hyhc2:

• d1hyhc2 first appeared (with stable ids) in SCOP 1.55
  
• d1hyhc2 appears in SCOP 1.65
  
• d1hyhc2 appears in SCOP 1.69
  
• d1hyhc2 appears in the current release, SCOPe 2.08