SCOPe 2.08: Domain d7dbke2: 7dbk E:162-334

Lineage for d7dbke2 (7dbk E:162-334)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (20 species)

7. Species Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [64444] (4 PDB entries)

8. Domain d7dbke2: 7dbk E:162-334 [421049]
   Other proteins in same PDB: d7dbka1, d7dbkb1, d7dbkc1, d7dbkd1, d7dbke1, d7dbkf1, d7dbkg1, d7dbkh1
   automated match to d1i0za2
   complexed with gol, nai

Details for d7dbke2

PDB Entry: 7dbk, 1.8 Å

PDB Description: crystal structure of human ldhb in complex with nadh

PDB Compounds: (E:) L-lactate dehydrogenase B chain

SCOPe Domain Sequences for d7dbke2:

Sequence; same for both SEQRES and ATOM records:

>d7dbke2 d.162.1.1 (E:162-334) Lactate dehydrogenase {Human (Homo sapiens), heart isoform (H chain) [TaxId: 9606]}
sgcnldsarfrylmaeklgihpsschgwilgehgdssvavwsgvnvagvslqelnpemgt
dndsenwkevhkmvvesayeviklkgytnwaiglsvadliesmlknlsrihpvstmvkgm
ygienevflslpcilnargltsvinqklkddevaqlkksadtlwdiqkdlkdl

Timeline for d7dbke2:

• d7dbke2 is new in SCOPe 2.08-stable