SCOP 1.67: Domain d1emd_2: 1emd 146-312

Lineage for d1emd_2 (1emd 146-312)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (2 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (4 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)

6. Protein Malate dehydrogenase [56329] (11 species)

7. Species Escherichia coli [TaxId:562] [56333] (4 PDB entries)

8. Domain d1emd_2: 1emd 146-312 [42103]
   Other proteins in same PDB: d1emd_1
   complexed with cit, nad

Details for d1emd_2

PDB Entry: 1emd, 1.9 Å

PDB Description: crystal structure of a ternary complex of escherichia coli malate dehydrogenase, citrate and nad at 1.9 angstroms resolution

SCOP Domain Sequences for d1emd_2:

Sequence; same for both SEQRES and ATOM records:

>d1emd_2 d.162.1.1 (146-312) Malate dehydrogenase {Escherichia coli}
vttldiirsntfvaelkgkqpgevevpvigghsgvtilpllsqvpgvsfteqevadltkr
iqnagtevveakagggsatlsmgqaaarfglslvralqgeqgvvecayvegdgqyarffs
qplllgkngveerksigtlsafeqnalegmldtlkkdialgqefvnk

Timeline for d1emd_2:

• d1emd_2 first appeared (with stable ids) in SCOP 1.55
  
• d1emd_2 appears in SCOP 1.65
  
• d1emd_2 appears in SCOP 1.69
  
• d1emd_2 appears in the current release, SCOPe 2.08, called d1emda2