SCOPe 2.06: Domain d5mdha2: 5mdh A:155-333

Lineage for d5mdha2 (5mdh A:155-333)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Malate dehydrogenase [56329] (12 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)

8. Domain d5mdha2: 5mdh A:155-333 [42093]
   Other proteins in same PDB: d5mdha1, d5mdhb1
   complexed with mak, nad

Details for d5mdha2

PDB Entry: 5mdh, 2.4 Å

PDB Description: crystal structure of ternary complex of porcine cytoplasmic malate dehydrogenase alpha-ketomalonate and tnad at 2.4 angstroms resolution

PDB Compounds: (A:) malate dehydrogenase

SCOPe Domain Sequences for d5mdha2:

Sequence; same for both SEQRES and ATOM records:

>d5mdha2 d.162.1.1 (A:155-333) Malate dehydrogenase {Pig (Sus scrofa) [TaxId: 9823]}
trldhnrakaqialklgvtsddvknviiwgnhsstqypdvnhakvklqakevgvyeavkd
dswlkgefittvqqrgaavikarklssamsaakaicdhvrdiwfgtpegefvsmgiisdg
nsygvpddllysfpvtikdktwkiveglpindfsrekmdltakelaeeketafeflssa

Timeline for d5mdha2:

• d5mdha2 first appeared (with stable ids) in SCOP 1.55
  
• d5mdha2 appears in SCOPe 2.05
  
• d5mdha2 appears in SCOPe 2.07
  
• d5mdha2 appears in the current release, SCOPe 2.08