Lineage for d7b7sc_ (7b7s C:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2980461Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2980462Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
    Uniprot P24941
  8. 3084493Domain d7b7sc_: 7b7s C: [420810]
    Other proteins in same PDB: d7b7sb1, d7b7sb2, d7b7sd1, d7b7sd2
    automated match to d6q49a_
    complexed with no3, sgm, so4, t1t

Details for d7b7sc_

PDB Entry: 7b7s (more details), 2.54 Å

PDB Description: cdk2/cyclin a2 in complex with 3h-pyrazolo[4,3-f]quinoline-based derivative hsd1368
PDB Compounds: (C:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d7b7sc_:

Sequence, based on SEQRES records: (download)

>d7b7sc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv

Sequence, based on observed residues (ATOM records): (download)

>d7b7sc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtgvvykarnkltgevvalkkirldtegvpstaireisllkelnhpni
vklldvihnklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
rdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavd
iwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwar
qdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv

SCOPe Domain Coordinates for d7b7sc_:

Click to download the PDB-style file with coordinates for d7b7sc_.
(The format of our PDB-style files is described here.)

Timeline for d7b7sc_:

  • d7b7sc_ is new in SCOPe 2.08-stable