SCOP 1.57: Domain d2fgib_: 2fgi B:

Lineage for d2fgib_ (2fgi B:)

1. Root: SCOP 1.57

2. Class d: Alpha and beta proteins (a+b) [53931] (194 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)

5. Family d.144.1.2: Tyrosine kinase [56150] (9 proteins)

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (4 PDB entries)

8. Domain d2fgib_: 2fgi B: [41700]

Details for d2fgib_

PDB Entry: 2fgi, 2.5 Å

PDB Description: crystal structure of the tyrosine kinase domain of fgf receptor 1 in complex with inhibitor pd173074

SCOP Domain Sequences for d2fgib_:

Sequence, based on SEQRES records:

>d2fgib_ d.144.1.2 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens)}
seyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksda
tekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppg
leysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkia
dfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggsp
ypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrival
t

Sequence, based on observed residues (ATOM records):

>d2fgib_ d.144.1.2 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens)}
seyelpedprwelprdrlvlgkplgegafgqvvlaeaiglpnrvtkvavkmlksdatekd
lsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrqlsskdl
vscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgladyykkgrlpvkwmap
ealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsnctnel
ymmmrdcwhavpsqrptfkqlvedldrivalt

Timeline for d2fgib_:

• d2fgib_ first appeared (with stable ids) in SCOP 1.55
  
• d2fgib_ appears in SCOP 1.59
  
• d2fgib_ appears in the current release, SCOPe 2.08