SCOP 1.63: Domain d2fgia_: 2fgi A:

Lineage for d2fgia_ (2fgi A:)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.2: Tyrosine kinase [56150] (15 proteins)

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (4 PDB entries)

8. Domain d2fgia_: 2fgi A: [41699]

Details for d2fgia_

PDB Entry: 2fgi, 2.5 Å

PDB Description: crystal structure of the tyrosine kinase domain of fgf receptor 1 in complex with inhibitor pd173074

SCOP Domain Sequences for d2fgia_:

Sequence, based on SEQRES records:

>d2fgia_ d.144.1.2 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens)}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Sequence, based on observed residues (ATOM records):

>d2fgia_ d.144.1.2 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens)}
elpedprwelprdrlvlgkplgqvvlaeaiglpnrvtkvavkmlksdatekdlsdlisem
emmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppqlsskdlvscayq
vargmeylaskkcihrdlaarnvlvtednvmkiadfgladihhidyykktngrlpvkwma
pealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsnctne
lymmmrdcwhavpsqrptfkqlvedldrivalts

Timeline for d2fgia_:

• d2fgia_ first appeared (with stable ids) in SCOP 1.55
  
• d2fgia_ appears in SCOP 1.61
  
• d2fgia_ appears in SCOP 1.65
  
• d2fgia_ appears in the current release, SCOPe 2.08