SCOP 1.65: Domain d1agwa_: 1agw A:

Lineage for d1agwa_ (1agw A:)

1. Root: SCOP 1.65

2. Class d: Alpha and beta proteins (a+b) [53931] (234 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (41 proteins)
   members organised in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (4 PDB entries)

8. Domain d1agwa_: 1agw A: [41695]

Details for d1agwa_

PDB Entry: 1agw, 2.4 Å

PDB Description: crystal structure of the tyrosine kinase domain of fibroblast growth factor receptor 1 in complex with su4984 inhibitor

SCOP Domain Sequences for d1agwa_:

Sequence, based on SEQRES records:

>d1agwa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens)}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Sequence, based on observed residues (ATOM records):

>d1agwa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens)}
elpedprwelprdrlvlgkplgqvvlaeaiglpnrvtkvavkmlksdatekdlsdlisem
emmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppeeqlsskdlvsca
yqvargmeylaskkcihrdlaarnvlvtednvmkiadfglardihhidyykkttngrlpv
kwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsn
ctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Timeline for d1agwa_:

• d1agwa_ first appeared (with stable ids) in SCOP 1.55
  
• d1agwa_ appears in SCOP 1.63
  
• d1agwa_ appears in SCOP 1.67
  
• d1agwa_ appears in the current release, SCOPe 2.08