SCOPe 2.02: Domain d1fgka_: 1fgk A:

Lineage for d1fgka_ (1fgk A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (9 PDB entries)

8. Domain d1fgka_: 1fgk A: [41693]

Details for d1fgka_

PDB Entry: 1fgk, 2 Å

PDB Description: crystal structure of the tyrosine kinase domain of fibroblast growth factor receptor 1

PDB Compounds: (A:) fgf receptor 1

SCOPe Domain Sequences for d1fgka_:

Sequence, based on SEQRES records:

>d1fgka_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Sequence, based on observed residues (ATOM records):

>d1fgka_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgqvvlaeaiglpnrvtkvavkmlksdatekdlsdlisem
emmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppeeqlsskdlvsca
yqvargmeylaskkcihrdlaarnvlvtednvmkiadfglardihhidyykkttngrlpv
kwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsn
ctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Timeline for d1fgka_:

• d1fgka_ first appeared (with stable ids) in SCOP 1.55
  
• d1fgka_ appears in SCOPe 2.01
  
• d1fgka_ appears in SCOPe 2.03
  
• d1fgka_ appears in the current release, SCOPe 2.08