SCOPe 2.02: Domain d2ptka3: 2ptk A:249-528

Lineage for d2ptka3 (2ptk A:249-528)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (2 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (1 PDB entry)

8. Domain d2ptka3: 2ptk A:249-528 [41692]
   Other proteins in same PDB: d2ptka1, d2ptka2

Details for d2ptka3

PDB Entry: 2ptk, 2.35 Å

PDB Description: chicken src tyrosine kinase

PDB Compounds: (A:) Tyrosine-protein kinase transforming protein Src

SCOPe Domain Sequences for d2ptka3:

Sequence, based on SEQRES records:

>d2ptka3 d.144.1.7 (A:249-528) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
kpqtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgnmspeafl
qeaqvmkklrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaa
qiasgmayvermnyvhrdlraanilvgenlvckvadfglgrliedneytarqgakfpikw
tapeaalygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecp
eslhdlmcqcwrkdpeerptfeylqafledyftstepqyq

Sequence, based on observed residues (ATOM records):

>d2ptka3 d.144.1.7 (A:249-528) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
kpqtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkppeaflqeaq
vmkklrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqias
gmayvermnyvhrdlraanilvgenlvckvadfglfpikwtapeaalygrftiksdvwsf
gilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerpt
feylqafledyftstepqyq

Timeline for d2ptka3:

• d2ptka3 first appeared (with stable ids) in SCOP 1.55, called d2ptk_3
  
• d2ptka3 appears in SCOPe 2.01
  
• d2ptka3 appears in SCOPe 2.03
  
• d2ptka3 appears in the current release, SCOPe 2.08