Lineage for d1qcfa3 (1qcf A:249-531)

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 262793Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 262794Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 263016Family d.144.1.2: Tyrosine kinase [56150] (15 proteins)
  6. 263066Protein Haemopoetic cell kinase Hck [56151] (1 species)
    member of Src family
  7. 263067Species Human (Homo sapiens) [TaxId:9606] [56152] (3 PDB entries)
  8. 263068Domain d1qcfa3: 1qcf A:249-531 [41680]
    Other proteins in same PDB: d1qcfa1, d1qcfa2
    SH2 domain- and SH3 domain-binding regulatory tails are included
    complexed with pp1; mutant

Details for d1qcfa3

PDB Entry: 1qcf (more details), 2 Å

PDB Description: crystal structure of hck in complex with a src family-selective tyrosine kinase inhibitor

SCOP Domain Sequences for d1qcfa3:

Sequence; same for both SEQRES and ATOM records: (download)

>d1qcfa3 d.144.1.2 (A:249-531) Haemopoetic cell kinase Hck {Human (Homo sapiens)}
kpqkpwekdaweipreslklekklgagqfgevwmatynkhtkvavktmkpgsmsveafla
eanvmktlqhdklvklhavvtkepiyiitefmakgslldflksdegskqplpklidfsaq
iaegmafieqrnyihrdlraanilvsaslvckiadfglarviedneytaregakfpikwt
apeainfgsftiksdvwsfgillmeivtygripypgmsnpeviralergyrmprpencpe
elynimmrcwknrpeerptfeyiqsvlddfytatesqyeeip

SCOP Domain Coordinates for d1qcfa3:

Click to download the PDB-style file with coordinates for d1qcfa3.
(The format of our PDB-style files is described here.)

Timeline for d1qcfa3: