SCOP 1.69: Domain d1b6cd_: 1b6c D:

Lineage for d1b6cd_ (1b6c D:)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (53 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Type I TGF-beta receptor R4 [56144] (1 species)
   TKL group; STKR subfamily; serine/threonine kinase; possible evolutionary link to tyrosine kinases

7. Species Human (Homo sapiens) [TaxId:9606] [56145] (4 PDB entries)

8. Domain d1b6cd_: 1b6c D: [41674]
   Other proteins in same PDB: d1b6ca_, d1b6cc_, d1b6ce_, d1b6cg_

Details for d1b6cd_

PDB Entry: 1b6c, 2.6 Å

PDB Description: crystal structure of the cytoplasmic domain of the type i tgf-beta receptor in complex with fkbp12

SCOP Domain Sequences for d1b6cd_:

Sequence; same for both SEQRES and ATOM records:

>d1b6cd_ d.144.1.7 (D:) Type I TGF-beta receptor R4 {Human (Homo sapiens)}
ttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwrgkwrgeevavkif
ssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsdyhehgslfdylnr
ytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilvkkngtcciadlgl
avrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradiyamglvfweiarr
csiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqscealrvmakimrec
wyangaarltalrikktlsqlsqqeg

Timeline for d1b6cd_:

• d1b6cd_ first appeared (with stable ids) in SCOP 1.55
  
• d1b6cd_ appears in SCOP 1.67
  
• d1b6cd_ appears in SCOP 1.71
  
• d1b6cd_ appears in the current release, SCOPe 2.08