SCOP 1.59: Domain d1pme__: 1pme -

Lineage for d1pme__ (1pme -)

1. Root: SCOP 1.59

2. Class d: Alpha and beta proteins (a+b) [53931] (208 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)

5. Family d.144.1.1: Serine/threonin kinases [56113] (17 proteins)

6. Protein MAP kinase Erk2 [56134] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56135] (1 PDB entry)

8. Domain d1pme__: 1pme - [41653]

Details for d1pme__

PDB Entry: 1pme, 2 Å

PDB Description: structure of penta mutant human erk2 map kinase complexed with a specific inhibitor of human p38 map kinase

SCOP Domain Sequences for d1pme__:

Sequence, based on SEQRES records:

>d1pme__ d.144.1.1 (-) MAP kinase Erk2 {Human (Homo sapiens)}
gqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlreikil
lrfrheniigindiiraptieqmkdvylvthlmgadlykllktqhlsndhicyflyqilr
glkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrwyra
peimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnci
inlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleq
yydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyrs

Sequence, based on observed residues (ATOM records):

>d1pme__ d.144.1.1 (-) MAP kinase Erk2 {Human (Homo sapiens)}
gqvfdvgprytnlsyigygmvcsaydnvnkvrvaikkispfehqtycqrtlreikillrf
rheniigindiiraptieqmkdvylvthlmgadlykllktqhlsndhicyflyqilrglk
yihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrwyrapei
mlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinl
karnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyyd
psdepiaeapflpkeklkelifeetarfqpgyrs

Timeline for d1pme__:

• d1pme__ first appeared (with stable ids) in SCOP 1.55
  
• d1pme__ appears in SCOP 1.57
  
• d1pme__ appears in SCOP 1.61
  
• d1pme__ appears in the current release, SCOPe 2.08, called d1pmea_