Lineage for d1bi7a_ (1bi7 A:)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874749Protein Cyclin-dependent PK, CDK6 [88859] (1 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 874750Species Human (Homo sapiens) [TaxId:9606] [88860] (8 PDB entries)
  8. 874760Domain d1bi7a_: 1bi7 A: [41619]
    Other proteins in same PDB: d1bi7b_

Details for d1bi7a_

PDB Entry: 1bi7 (more details), 3.4 Å

PDB Description: mechanism of g1 cyclin dependent kinase inhibition from the structure of the cdk6-p16ink4a tumor suppressor complex
PDB Compounds: (A:) cyclin-dependent kinase 6

SCOP Domain Sequences for d1bi7a_:

Sequence, based on SEQRES records: (download)

>d1bi7a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK6 {Human (Homo sapiens) [TaxId: 9606]}
dqqyecvaeigegaygkvfkardlknggrfvalkrvrvqtgeegmplstirevavlrhle
tfehpnvvrlfdvctvsrtdretkltlvfehvdqdlttyldkvpepgvptetikdmmfql
lrgldflhshrvvhrdlkpqnilvtssgqikladfglariysfqmaltsvvvtlwyrape
vllqssyatpvdlwsvgcifaemfrrkplfrgssdvdqlgkildviglpgeedwprdval
prqafhsksaqpiekfvtdidelgkdlllkcltfnpakrisaysalshpyfq

Sequence, based on observed residues (ATOM records): (download)

>d1bi7a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK6 {Human (Homo sapiens) [TaxId: 9606]}
dqqyecvaeigegaygkvfkardlknggrfvalkrvrvqehpnvvrlfdvctvsrtdret
kltlvfehvdqdlttyldkvpepgvptetikdmmfqllrgldflhshrvvhrdlkpqnil
vtssgqikladfglariysfqmaltsvvvtlwyrapevllqssyatpvdlwsvgcifaem
frrkplfrgssdvdqlgkildviglpgeedwprdvalprqafhsksaqpiekfvtdidel
gkdlllkcltfnpakrisaysalshpyfq

SCOP Domain Coordinates for d1bi7a_:

Click to download the PDB-style file with coordinates for d1bi7a_.
(The format of our PDB-style files is described here.)

Timeline for d1bi7a_:

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d1bi7b_