SCOP 1.69: Domain d1b59a2: 1b59 A:110-374,A:449-478

Lineage for d1b59a2 (1b59 A:110-374,A:449-478)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.127: Creatinase/aminopeptidase [55919] (1 superfamily)
   duplication: composed of two very similar alpha+beta folds

4. Superfamily d.127.1: Creatinase/aminopeptidase [55920] (1 family)

5. Family d.127.1.1: Creatinase/aminopeptidase [55921] (3 proteins)

6. Protein Methionine aminopeptidase [55924] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55927] (7 PDB entries)
   methionine aminopeptidase 2 contains insert domain with a circularly permuted "winged helix" fold

8. Domain d1b59a2: 1b59 A:110-374,A:449-478 [41162]
   Other proteins in same PDB: d1b59a1

Details for d1b59a2

PDB Entry: 1b59, 1.8 Å

PDB Description: complex of human methionine aminopeptidase-2 complexed with ovalicin

SCOP Domain Sequences for d1b59a2:

Sequence, based on SEQRES records:

>d1b59a2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens)}
kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndf
reaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnnca
ahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgik
cagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpivkg
geatrmeegevyaietfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Sequence, based on observed residues (ATOM records):

>d1b59a2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens)}
kvqtdppsvpicdlypngvfpkgqeceypeekkaldqaseeiwndfreaaeahrqvrkyv
mswikpgmtmieicekledcsrklikenglnaglafptgcslnncaahytpnagdttvlq
yddickidfgthisgriidcaftvtfnpkydtllkavkdatntgikcagidvrlcdvgea
iqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpivkggeatrmeegevyai
etfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Timeline for d1b59a2:

• d1b59a2 first appeared (with stable ids) in SCOP 1.55
  
• d1b59a2 appears in SCOP 1.67
  
• d1b59a2 appears in SCOP 1.71
  
• d1b59a2 appears in the current release, SCOPe 2.08