SCOPe 2.07: Domain d6tgwa_: 6tgw A:

Lineage for d6tgwa_ (6tgw A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (59 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225691] (37 PDB entries)

8. Domain d6tgwa_: 6tgw A: [407176]
   automated match to d3u4jb_
   complexed with n98, nad

Details for d6tgwa_

PDB Entry: 6tgw, 2.8 Å

PDB Description: crystal structure of human aldehyde dehydrogenase 1a3 in complex with a selective inhibitor

PDB Compounds: (A:) Aldehyde dehydrogenase family 1 member A3

SCOPe Domain Sequences for d6tgwa_:

Sequence, based on SEQRES records:

>d6tgwa_ c.82.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
levkftkifinnewhesksgkkfatcnpstreqiceveegdkpdvdkaveaaqvafqrgs
pwrrldalsrgrllhqladlverdratlaaletmdtgkpflhaffidlegcirtlryfag
wadkiqgktiptddnvvcftrhepigvcgaitpwnfpllmlvwklapalccgntmvlkpa
eqtpltalylgslikeagfppgvvnivpgfgptvgaaisshpqinkiaftgstevgklvk
eaasrsnlkrvtlelggknpcivcadadldlavecahqgvffnqgqcctaasrvfveeqv
ysefvrrsveyakkrpvgdpfdvkteqgpqidqkqfdkileliesgkkegaklecggsam
edkglfikptvfsevtdnmriakeeifgpvqpilkfksieevikranstdygltaavftk
nldkalklasalesgtvwincynalyaqapfggfkmsgngrelgeyalaeytevktvtik
l

Sequence, based on observed residues (ATOM records):

>d6tgwa_ c.82.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
levkftkifinnewhesksgkkfatcnpstreqiceveegdkpdvdkaveaaqvafqrgs
pwrrldalsrgrllhqladlverdratlaaletmdtgkpflhaffidlegcirtlryfag
wadkiqgktiptddnvvcftrhepigvcgaitpwnfpllmlvwklapalccgntmvlkpa
eqtpltalylgslikeagfppgvvnivpgfgptvgaaisshpqinkiaftgstevgklvk
eaasrsnlkrvtlelggknpcivcadadldlavecahqgvffnqgqcctaasrvfveeqv
ysefvrrsveyakkrpvgdpfdvkteqgpqidqkqfdkileliesgkkegaklecggsam
glfikptvfsevtdnmriakeeifgpvqpilkfksieevikranstdygltaavftknld
kalklasalesgtvwincynalyaqapfggfkmsgngrelgeyalaeytevktvtikl

Timeline for d6tgwa_:

• d6tgwa_ is new in SCOPe 2.07-stable
  
• d6tgwa_ appears in the current release, SCOPe 2.08