SCOPe 2.07: Domain d7mtxe1: 7mtx E:1-486

Lineage for d7mtxe1 (7mtx E:1-486)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (15 species)
   not a true protein

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [330485] (8 PDB entries)

8. Domain d7mtxe1: 7mtx E:1-486 [405674]
   Other proteins in same PDB: d7mtxa2, d7mtxb2, d7mtxc2, d7mtxd2, d7mtxe2, d7mtxf2, d7mtxg2, d7mtxh2
   automated match to d5uwxb_
   complexed with imp, k, zo4

Details for d7mtxe1

PDB Entry: 7mtx, 2.44 Å

PDB Description: crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from bacillus anthracis in the complex with imp and the inhibitor p176

PDB Compounds: (E:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d7mtxe1:

Sequence, based on SEQRES records:

>d7mtxe1 c.1.5.0 (E:1-486) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvteadma
iamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasvda
ivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpgsi
cttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgsmf
agvaespgeteiyqgrqfkvyrgmgsvgamekgskdryfqegnkklvpegiegrvpykgp
ladtvhqlvgglragmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapnys

Sequence, based on observed residues (ATOM records):

>d7mtxe1 c.1.5.0 (E:1-486) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvteadma
iamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasvda
ivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpgsi
cttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgsmf
agvaespgeteiyqgrqfkvyrgmgsvgamekkklvpegiegrvpykgpladtvhqlvgg
lragmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapnys

Timeline for d7mtxe1:

• d7mtxe1 is new in SCOPe 2.07-stable
  
• d7mtxe1 appears in the current release, SCOPe 2.08