Lineage for d2shpb3 (2shp B:111-218)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2206459Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
  4. 2206460Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 2206461Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 2206866Protein Tyrosine phoshatase shp-2 [55589] (1 species)
  7. 2206867Species Human (Homo sapiens) [TaxId:9606] [55590] (1 PDB entry)
  8. 2206871Domain d2shpb3: 2shp B:111-218 [40536]
    Other proteins in same PDB: d2shpa1, d2shpb1
    complexed with cat

Details for d2shpb3

PDB Entry: 2shp (more details), 2 Å

PDB Description: tyrosine phosphatase shp-2
PDB Compounds: (B:) shp-2

SCOPe Domain Sequences for d2shpb3:

Sequence, based on SEQRES records: (download)

>d2shpb3 d.93.1.1 (B:111-218) Tyrosine phoshatase shp-2 {Human (Homo sapiens) [TaxId: 9606]}
rwfhghlsgkeaeklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthv
mircqelkydvgggerfdsltdlvehykknpmvetlgtvlqlkqplnt

Sequence, based on observed residues (ATOM records): (download)

>d2shpb3 d.93.1.1 (B:111-218) Tyrosine phoshatase shp-2 {Human (Homo sapiens) [TaxId: 9606]}
rwfhghlsgkeaeklltekgkhgsflvresqshpgdfvlsvrtgdndgkskvthvmircq
elkydvgggerfdsltdlvehykknpmvetlgtvlqlkqplnt

SCOPe Domain Coordinates for d2shpb3:

Click to download the PDB-style file with coordinates for d2shpb3.
(The format of our PDB-style files is described here.)

Timeline for d2shpb3: