Lineage for d7kdba2 (7kdb A:126-251)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2582825Fold d.130: S-adenosylmethionine synthetase [55972] (1 superfamily)
    duplication: consists of 3 similar intertwined domains
    structural repeat: beta-alpha-beta(2)-alpha-beta; two layers, alpha/beta
  4. 2582826Superfamily d.130.1: S-adenosylmethionine synthetase [55973] (2 families) (S)
  5. 2582827Family d.130.1.1: S-adenosylmethionine synthetase [55974] (2 proteins)
  6. 2582828Protein S-adenosylmethionine synthetase [55975] (3 species)
    synonym: methionine adenosyltransferase, MAT
  7. 2582878Species Human (Homo sapiens), isoform type-2 [TaxId:9606] [160759] (8 PDB entries)
    Uniprot P31153 126-251! Uniprot P31153 16-125! Uniprot P31153 252-395
    MAT2A
  8. 2582892Domain d7kdba2: 7kdb A:126-251 [403407]
    automated match to d2p02a2
    complexed with cl, edo, gol, sam, trs, wbs

Details for d7kdba2

PDB Entry: 7kdb (more details), 1.24 Å

PDB Description: crystal structure of human methionine adenosyltransferase 2a (mat2a) in complex with sam and allosteric inhibitor compound 35
PDB Compounds: (A:) S-adenosylmethionine synthase isoform type-2

SCOPe Domain Sequences for d7kdba2:

Sequence; same for both SEQRES and ATOM records: (download)

>d7kdba2 d.130.1.1 (A:126-251) S-adenosylmethionine synthetase {Human (Homo sapiens), isoform type-2 [TaxId: 9606]}
needigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvt
vqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlq
psgrfv

SCOPe Domain Coordinates for d7kdba2:

Click to download the PDB-style file with coordinates for d7kdba2.
(The format of our PDB-style files is described here.)

Timeline for d7kdba2: