Lineage for d7dr4j_ (7dr4 J:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2318696Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2318697Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2318797Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. 2318856Protein Interleukin-2 (IL-2) [47301] (1 species)
  7. 2318857Species Human (Homo sapiens) [TaxId:9606] [47302] (19 PDB entries)
  8. 2318869Domain d7dr4j_: 7dr4 J: [403247]
    Other proteins in same PDB: d7dr4b1, d7dr4d1, d7dr4d2, d7dr4f1, d7dr4f2, d7dr4l1, d7dr4l2
    automated match to d1m48b_

Details for d7dr4j_

PDB Entry: 7dr4 (more details), 2.49 Å

PDB Description: complex of anti-human il-2 antibody and human il-2
PDB Compounds: (J:) interleukin-2

SCOPe Domain Sequences for d7dr4j_:

Sequence, based on SEQRES records: (download)

>d7dr4j_ a.26.1.2 (J:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
sstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelk
pleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwitf
cqsiistlt

Sequence, based on observed residues (ATOM records): (download)

>d7dr4j_ a.26.1.2 (J:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
sstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelk
pleevlnlaqsknfhlrprdlisninvivlelkgfmceyadetativeflnrwitfcqsi
istlt

SCOPe Domain Coordinates for d7dr4j_:

Click to download the PDB-style file with coordinates for d7dr4j_.
(The format of our PDB-style files is described here.)

Timeline for d7dr4j_: