SCOPe 2.08: Domain d7e34a1: 7e34 A:2-298

Lineage for d7e34a1 (7e34 A:2-298)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
   Uniprot P24941

8. Domain d7e34a1: 7e34 A:2-298 [403243]
   Other proteins in same PDB: d7e34a2
   automated match to d4fkla_
   complexed with gol, zn

Details for d7e34a1

PDB Entry: 7e34, 3.19 Å

PDB Description: crystal structure of sun1-speedy a-cdk2

PDB Compounds: (A:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d7e34a1:

Sequence; same for both SEQRES and ATOM records:

>d7e34a1 d.144.1.7 (A:2-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
enfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnhp
nivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchsh
rvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyys
tavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfp
kwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d7e34a1:

• d7e34a1 first appeared in SCOPe 2.07