SCOPe 2.08: Domain d6vuga1: 6vug A:2-429

Lineage for d6vuga1 (6vug A:2-429)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (4 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (206 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d6vuga1: 6vug A:2-429 [400699]
   Other proteins in same PDB: d6vuga2, d6vugc1, d6vugc2, d6vugd_
   automated match to d2be2a1
   complexed with gol, so4

Details for d6vuga1

PDB Entry: 6vug, 3 Å

PDB Description: diabody bound to a reverse transcriptase aptamer complex

PDB Compounds: (A:) Reverse transcriptase/ribonuclease H

SCOPe Domain Sequences for d6vuga1:

Sequence, based on SEQRES records:

>d6vuga1 e.8.1.2 (A:2-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvf
aikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpld
edfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviy
qymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtv
qpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeael
elaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgah
tndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpp
lvklwyql

Sequence, based on observed residues (ATOM records):

>d6vuga1 e.8.1.2 (A:2-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskinpyntpvfaik
kkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyt
aftiiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsdleigq
hrtkieelrqhllrwglttpdkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiq
klvgklnwasqiypgikvrqlskllrkalteviplteeaelelaenreilkepvhgvyyd
pskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesi
viwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql

Timeline for d6vuga1:

• d6vuga1 first appeared in SCOPe 2.07