SCOPe 2.08: Domain d7cmdb2: 7cmd B:62-315

Lineage for d7cmdb2 (7cmd B:62-315)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.23: Papain-like viral protease catalytic domain [310648] (2 proteins)
   C-terminal part of Pfam PF08715

6. Protein automated matches [310868] (6 species)
   not a true protein

7. Species Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049] [385225] (34 PDB entries)

8. Domain d7cmdb2: 7cmd B:62-315 [389993]
   Other proteins in same PDB: d7cmda1, d7cmda3, d7cmdb1, d7cmdb3, d7cmdc1, d7cmdc3, d7cmdd1, d7cmdd3
   automated match to d4m0wa2
   complexed with ttt, zn

Details for d7cmdb2

PDB Entry: 7cmd, 2.59 Å

PDB Description: crystal structure of the sars-cov-2 plpro with grl0617

PDB Compounds: (B:) non-structural protein 3

SCOPe Domain Sequences for d7cmdb2:

Sequence, based on SEQRES records:

>d7cmdb2 d.3.1.23 (B:62-315) automated matches {Severe acute respiratory syndrome coronavirus 2 [TaxId: 2697049]}
dtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnncylatalltlq
qielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhanldsc
krvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqqespf
vmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseykgpit
dvfykensytttik

Sequence, based on observed residues (ATOM records):

>d7cmdb2 d.3.1.23 (B:62-315) automated matches {Severe acute respiratory syndrome coronavirus 2 [TaxId: 2697049]}
dtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnncylatalltlq
qielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhanldsc
krvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqitkylvqqespfvmmsappa
qyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseykgpitdvfykens
ytttik

Timeline for d7cmdb2:

• d7cmdb2 first appeared in SCOPe 2.07