SCOPe 2.08: Domain d6x2va_: 6x2v A:

Lineage for d6x2va_ (6x2v A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Ran [52609] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52611] (90 PDB entries)

8. Domain d6x2va_: 6x2v A: [388750]
   Other proteins in same PDB: d6x2vb_
   automated match to d1k5da_
   complexed with gnp, gol, mg
   has additional insertions and/or extensions that are not grouped together

Details for d6x2va_

PDB Entry: 6x2v, 2.82 Å

PDB Description: crystal structure of pki(de)nes peptide bound to crm1

PDB Compounds: (A:) GTP-binding nuclear protein ran

SCOPe Domain Sequences for d6x2va_:

Sequence, based on SEQRES records:

>d6x2va_ c.37.1.8 (A:) Ran {Human (Homo sapiens) [TaxId: 9606]}
vqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdtag
qekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdikd
rkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappevv
mdpalaaqyehdlevaqttalpdedddl

Sequence, based on observed residues (ATOM records):

>d6x2va_ c.37.1.8 (A:) Ran {Human (Homo sapiens) [TaxId: 9606]}
vqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdtag
qekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdikd
rkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappela
aqyehdlevaqttalpdedddl

Timeline for d6x2va_:

• d6x2va_ first appeared in SCOPe 2.07