SCOPe 2.08: Domain d6vn2a_: 6vn2 A:

Lineage for d6vn2a_ (6vn2 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (6 proteins)
   Pfam PF00443

6. Protein Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) [82569] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82570] (25 PDB entries)

8. Domain d6vn2a_: 6vn2 A: [384926]
   automated match to d1nb8b_
   complexed with act, r44

Details for d6vn2a_

PDB Entry: 6vn2, 2.93 Å

PDB Description: usp7 in complex with ligand compound 18

PDB Compounds: (A:) Ubiquitin carboxyl-terminal hydrolase 7

SCOPe Domain Sequences for d6vn2a_:

Sequence, based on SEQRES records:

>d6vn2a_ d.3.1.9 (A:) Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) {Human (Homo sapiens) [TaxId: 9606]}
skkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfye
lqhsdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfrg
kmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehgl
qeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpa
nyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddls
vrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk

Sequence, based on observed residues (ATOM records):

>d6vn2a_ d.3.1.9 (A:) Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) {Human (Homo sapiens) [TaxId: 9606]}
skkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfye
lqhsdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfrg
kmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehgl
qeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpa
nyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghddtna
ymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk

Timeline for d6vn2a_:

• d6vn2a_ first appeared in SCOPe 2.07