SCOPe 2.06: Domain d1fkia_: 1fki A:

Lineage for d1fkia_ (1fki A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.26: FKBP-like [54533] (3 superfamilies)
   core: beta(2)-alpha-beta(2); antiparallel beta-sheet

4. Superfamily d.26.1: FKBP-like [54534] (4 families)

5. Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 proteins)

6. Protein FK-506 binding protein (FKBP12), an immunophilin [54536] (2 species)
   cis-trans prolyl-isomerase

7. Species Human (Homo sapiens) [TaxId:9606] [54537] (42 PDB entries)

8. Domain d1fkia_: 1fki A: [38401]
   complexed with sb1

Details for d1fkia_

PDB Entry: 1fki, 2.2 Å

PDB Description: design, synthesis, and kinetic evaluation of high-affinity fkbp ligands, and the x-ray crystal structures of their complexes with fkbp12

PDB Compounds: (A:) fk506 binding protein

SCOPe Domain Sequences for d1fkia_:

Sequence; same for both SEQRES and ATOM records:

>d1fkia_ d.26.1.1 (A:) FK-506 binding protein (FKBP12), an immunophilin {Human (Homo sapiens) [TaxId: 9606]}
gvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgwe
egvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle

Timeline for d1fkia_:

• d1fkia_ first appeared (with stable ids) in SCOP 1.55
  
• d1fkia_ appears in SCOPe 2.05
  
• d1fkia_ appears in SCOPe 2.07
  
• d1fkia_ appears in the current release, SCOPe 2.08