SCOPe 2.03: Domain d1hsba2: 1hsb A:1-181

Lineage for d1hsba2 (1hsb A:1-181)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (2 families)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (28 species)

7. Species Human (Homo sapiens), HLA-AW68 [TaxId:9606] [54472] (3 PDB entries)

8. Domain d1hsba2: 1hsb A:1-181 [38257]
   Other proteins in same PDB: d1hsba1, d1hsbb_
   complexed with ala, arg

Details for d1hsba2

PDB Entry: 1hsb, 1.9 Å

PDB Description: different length peptides bind to hla-aw68 similarly at their ends but bulge out in the middle

PDB Compounds: (A:) class I histocompatibility antigen (hla-aw68.1)

SCOPe Domain Sequences for d1hsba2:

Sequence; same for both SEQRES and ATOM records:

>d1hsba2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-AW68 [TaxId: 9606]}
gshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
drntrnvkaqsqtdrvdlgtlrgyynqseagshtiqmmygcdvgsdgrflrgyrqdaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqwraylegtcvewlrrylengketlq
r

Timeline for d1hsba2:

• d1hsba2 first appeared (with stable ids) in SCOP 1.55
  
• d1hsba2 appears in SCOPe 2.02
  
• d1hsba2 appears in SCOPe 2.04
  
• d1hsba2 appears in the current release, SCOPe 2.08