SCOPe 2.08: Domain d6lvse_: 6lvs E:

Lineage for d6lvse_ (6lvs E:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (6 proteins)
   Pfam PF00443

6. Protein Ubiquitin carboxyl-terminal hydrolase 14 [142860] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142861] (7 PDB entries)
   Uniprot P54578 100-482

8. Domain d6lvse_: 6lvs E: [382302]
   automated match to d2ayna1
   complexed with bme, edo, fmt, gol, na; mutant

Details for d6lvse_

PDB Entry: 6lvs, 2.73 Å

PDB Description: usp14 catalytic domain mutant c114s

PDB Compounds: (E:) Ubiquitin carboxyl-terminal hydrolase 14

SCOPe Domain Sequences for d6lvse_:

Sequence, based on SEQRES records:

>d6lvse_ d.3.1.9 (E:) Ubiquitin carboxyl-terminal hydrolase 14 {Human (Homo sapiens) [TaxId: 9606]}
lpcgltnlgntsymnatvqcirsvpelkdalkryagalrasgemasaqyitaalrdlfds
mdktsssippiillqflhmafpqfaekgeqgqylqqdanecwiqmmrvlqqkleaiedds
saatpskkkslidqffgvefettmkcteseeeevtkgkenqlqlscfinqevkylftglk
lrlqeeitkqsptlqrnalyiksskisrlpayltiqmvrffykekesvnakvlkdvkfpl
mldmyelctpelqekmvsfrskfkdledkkvnqqpntsdkksspqkevkyepfsfaddig
snncgyydlqavlthqgrssssghyvswvkrkqdewikfdddkvsivtpedilrlsgggd
whiayvllygprr

Sequence, based on observed residues (ATOM records):

>d6lvse_ d.3.1.9 (E:) Ubiquitin carboxyl-terminal hydrolase 14 {Human (Homo sapiens) [TaxId: 9606]}
lpcgltnlgntsymnatvqcirsvpelkdalkryagalrasgemasaqyitaalrdlfds
mdktsssippiillqflhmafpqfaekgeqgqylqqdanecwiqmmrvlqqkleaieksl
idqffgvefettmkcteeevtkgkenqlqlscfinqevkylftglklrlqeeitkqsptl
qrnalyiksskisrlpayltiqmvrffyknakvlkdvkfplmldmyelctpelqekmvsf
rskfyepfsfaddigsnncgyydlqavlthqgrssssghyvswvkrkqdewikfdddkvs
ivtpedilrlsgggdwhiayvllygprr

Timeline for d6lvse_:

• d6lvse_ first appeared in SCOPe 2.07