SCOP 1.75: Domain d2clrd2: 2clr D:1-181

Lineage for d2clrd2 (2clr D:1-181)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (1 family)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (12 proteins)

6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (27 species)

7. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (76 PDB entries)
   Uniprot P01892 25-298

8. Domain d2clrd2: 2clr D:1-181 [38229]
   Other proteins in same PDB: d2clra1, d2clrb_, d2clrd1, d2clre_

Details for d2clrd2

PDB Entry: 2clr, 2 Å

PDB Description: three dimensional structure of a peptide extending out one end of a class i mhc binding site

PDB Compounds: (D:) class I histocompatibility antigen (hla-a 0201) (alpha chain)

SCOP Domain Sequences for d2clrd2:

Sequence; same for both SEQRES and ATOM records:

>d2clrd2 d.19.1.1 (D:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-A2.1 [TaxId: 9606]}
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
r

Timeline for d2clrd2:

• d2clrd2 first appeared (with stable ids) in SCOP 1.55
  
• d2clrd2 appears in SCOP 1.73
  
• d2clrd2 appears in SCOPe 2.01
  
• d2clrd2 appears in the current release, SCOPe 2.08