SCOPe 2.08: Domain d6gwpa_: 6gwp A:

Lineage for d6gwpa_ (6gwp A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein automated matches [190484] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188559] (24 PDB entries)

8. Domain d6gwpa_: 6gwp A: [378723]
   Other proteins in same PDB: d6gwpb_, d6gwpc_
   automated match to d1lj5a_

Details for d6gwpa_

PDB Entry: 6gwp, 2.28 Å

PDB Description: crystal structure of stabilized active plasminogen activator inhibitor-1 (pai-1-stab) in complex with two inhibitory nanobodies (vhh-2g-42, vhh-2w-64)

PDB Compounds: (A:) plasminogen activator inhibitor-1

SCOPe Domain Sequences for d6gwpa_:

Sequence, based on SEQRES records:

>d6gwpa_ e.1.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
syvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqaamgfk
iddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrstvkqvd
fseverarfiindwvkthtkgmishllgtgavdqltrlvlvnalyfngqwktpfpdssth
rrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaapyekev
plsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfrpfqad
ftslsdqeplhvalalqkvkievnesgtvassstavivsarmapeeiiidrpflfvvrhn
ptgtvlfmgqvmep

Sequence, based on observed residues (ATOM records):

>d6gwpa_ e.1.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
syvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqqiqaamgfk
iddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlfrstvkqvd
fseverarfiindwvkthtkgmishllgtgavdqltrlvlvnalyfngqwktpfpdssth
rrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfiaapyekev
plsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtdmfrpfqad
ftslsdqeplhvalalqkvkievnesgtavivsarmapeeiiidrpflfvvrhnptgtvl
fmgqvmep

Timeline for d6gwpa_:

• d6gwpa_ first appeared in SCOPe 2.07