SCOPe 2.08: Domain d6ea4b2: 6ea4 B:272-546

Lineage for d6ea4b2 (6ea4 B:272-546)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.0: automated matches [191495] (1 protein)
   not a true family

6. Protein automated matches [190805] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188286] (69 PDB entries)

8. Domain d6ea4b2: 6ea4 B:272-546 [378189]
   Other proteins in same PDB: d6ea4a1, d6ea4a3, d6ea4a4, d6ea4a5, d6ea4b1, d6ea4b3, d6ea4b4, d6ea4b5
   automated match to d3se6a2
   complexed with j2g, lys, mes, nag, zn

Details for d6ea4b2

PDB Entry: 6ea4, 2.45 Å

PDB Description: erap2 bound to aryl sulfonamide uncompetitive inhibitor

PDB Compounds: (B:) Endoplasmic reticulum aminopeptidase 2

SCOPe Domain Sequences for d6ea4b2:

Sequence, based on SEQRES records:

>d6ea4b2 d.92.1.0 (B:272-546) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hslsgftssgvkvsiyaspdkrnqthyalqaslklldfyekyfdiyyplskldliaipdf
apgamenwglityretsllfdpktssasdklwvtrviahelahqwfgnlvtmewwndiwl
negfakymeliavnatypelqfddyflnvcfevitkdslnssrpiskpaetptqiqemfd
evsynkgacilnmlkdflgeekfqkgiiqylkkfsyrnaknddlwsslsnsclesdftsg
gvchsdpkmtsnmlaflgenaevkemmttwtlqkg

Sequence, based on observed residues (ATOM records):

>d6ea4b2 d.92.1.0 (B:272-546) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hslsgftssgvkvsiyaspdkrnqthyalqaslklldfyekyfdiyyplskldliaipdf
apgamenwglityretsllfdpktssasdklwvtrviahelahqwfgnlvtmewwndiwl
negfakymeliavnatypelqfddyflnvcfevitkdslnssrpiskpaetptqiqemfd
evsynkgacilnmlkdflgeekfqkgiiqylkkfsyrnaknddlwsslsnvkemmttwtl
qkg

Timeline for d6ea4b2:

• d6ea4b2 first appeared in SCOPe 2.07