Lineage for d6mvad1 (6mva D:1-159)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2844315Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 2844354Protein Lactate dehydrogenase [51859] (19 species)
  7. 2844420Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (39 PDB entries)
  8. 2844494Domain d6mvad1: 6mva D:1-159 [376230]
    Other proteins in same PDB: d6mvaa2, d6mvab2, d6mvac2, d6mvad2
    automated match to d4jnka1
    complexed with d4s, epe, nai, so4

Details for d6mvad1

PDB Entry: 6mva (more details), 2.02 Å

PDB Description: ldha structure in complex with inhibitor 14
PDB Compounds: (D:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d6mvad1:

Sequence, based on SEQRES records: (download)

>d6mvad1 c.2.1.5 (D:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvig

Sequence, based on observed residues (ATOM records): (download)

>d6mvad1 c.2.1.5 (D:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitaganlvqrnvnifkfiipnvvkyspn
ckllivsnpvdiltyvawkisgfpknrvig

SCOPe Domain Coordinates for d6mvad1:

Click to download the PDB-style file with coordinates for d6mvad1.
(The format of our PDB-style files is described here.)

Timeline for d6mvad1: