SCOPe 2.08: Domain d6k9vf2: 6k9v F:77-378

Lineage for d6k9vf2 (6k9v F:77-378)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (11 families)

5. Family d.142.1.10: Tubulin tyrosine ligase (TTL) C-terminal domain-like [310626] (2 proteins)
   Pfam PF03133; PubMed 22020298

6. Protein Tubulin tyrosine ligase (TTL) C-terminal domain [310728] (3 species)

7. Species Chicken (Gallus gallus) [TaxId:9031] [311385] (176 PDB entries)

8. Domain d6k9vf2: 6k9v F:77-378 [373481]
   Other proteins in same PDB: d6k9va1, d6k9va2, d6k9vb1, d6k9vb2, d6k9vc1, d6k9vc2, d6k9vd1, d6k9vd2, d6k9ve_, d6k9vf1, d6k9vf3
   automated match to d3tiia2
   complexed with acp, ca, d3l, gdp, gtp, mes, mg

Details for d6k9vf2

PDB Entry: 6k9v, 2.54 Å

PDB Description: crystal structure of tubulin in complex with inhibitor d64

PDB Compounds: (F:) tubulin tyrosine ligase

SCOPe Domain Sequences for d6k9vf2:

Sequence, based on SEQRES records:

>d6k9vf2 d.142.1.10 (F:77-378) Tubulin tyrosine ligase (TTL) C-terminal domain {Chicken (Gallus gallus) [TaxId: 9031]}
lvkliktspelsesctwfpesyviyptnlktpvapaqngirhlinntrtderevflaayn
rrregregnvwiakssagakgegilisseaselldfideqgqvhviqkylekplllepgh
rkfdirswvlvdhlyniylyregvlrtssepynsanfqdktchltnhciqkeysknygry
eegnemffeefnqylmdalnttlensillqikhiirsclmciepaistkhlhyqsfqlfg
fdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfpladtgqktsqptsifi
kl

Sequence, based on observed residues (ATOM records):

>d6k9vf2 d.142.1.10 (F:77-378) Tubulin tyrosine ligase (TTL) C-terminal domain {Chicken (Gallus gallus) [TaxId: 9031]}
lvkliktspelsesctwfpesyviyptderevflaaynrrregregnvwialisseasel
ldfideqgqvhviqkylekplllepghrkfdirswvlvdhlyniylyregvlrtssepyn
sanfqdktchltnhciqknygryeegnemffeefnqylmdalnttlensillqikhiirs
clmciepaistkhlhyqsfqlfgfdfmvdeelkvwlievngapacaqklyaelcqgivdv
aissvfplatsifikl

Timeline for d6k9vf2:

• d6k9vf2 first appeared in SCOPe 2.07