SCOPe 2.08: Domain d6ojud1: 6oju D:30-313

Lineage for d6ojud1 (6oju D:30-313)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55840] (47 PDB entries)

8. Domain d6ojud1: 6oju D:30-313 [371136]
   Other proteins in same PDB: d6ojua2, d6ojub2, d6ojuc2, d6ojud2
   automated match to d1hzwa_
   complexed with d96, ump

Details for d6ojud1

PDB Entry: 6oju, 2.88 Å

PDB Description: crystal structure of human thymidylate synthase delta (7-29) in complex with dump and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3- d]pyrimidine-methyl-phenyl-d-glutamic acid

PDB Compounds: (D:) Thymidylate synthase,Thymidylate synthase

SCOPe Domain Sequences for d6ojud1:

Sequence; same for both SEQRES and ATOM records:

>d6ojud1 d.117.1.1 (D:30-313) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
elqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvleell
wfikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgaeyrdm
esdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvnsels
cqlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhieplkiql
qreprpfpklrilrkvekiddfkaedfqiegynphptikmemav

Timeline for d6ojud1:

• d6ojud1 first appeared in SCOPe 2.07, called d6ojud_