SCOP 1.71: Domain d1df0a3: 1df0 A:2-355

Lineage for d1df0a3 (1df0 A:2-355)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (12 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)

6. Protein Calpain large subunit, catalytic domain (domain II) [54041] (3 species)
   includes the N-terminal 'sequence' domain I

7. Species Rat (Rattus norvegicus), M-type [TaxId:10116] [54043] (2 PDB entries)

8. Domain d1df0a3: 1df0 A:2-355 [37106]
   Other proteins in same PDB: d1df0a1, d1df0a2, d1df0b_
   mutant

Details for d1df0a3

PDB Entry: 1df0, 2.6 Å

PDB Description: crystal structure of m-calpain

SCOP Domain Sequences for d1df0a3:

Sequence, based on SEQRES records:

>d1df0a3 d.3.1.3 (A:2-355) Calpain large subunit, catalytic domain (domain II) {Rat (Rattus norvegicus), M-type}
agiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpsfpalpsslgfk
elgpyssktrgiewkrpteicadpqfiiggatrtdicqgalgdswllaaiasltlneeil
arvvpldqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftggiaewyelrkpppnlfkiiqkalekgsllgcs
iditsaadseavtyqklvkghaysvtgaeevessgslqklirirnpwgqvewtgkwndnc
pswntvdpevranlterqedgefwmsfsdflrhysrleicnltpdtltcdsykk

Sequence, based on observed residues (ATOM records):

>d1df0a3 d.3.1.3 (A:2-355) Calpain large subunit, catalytic domain (domain II) {Rat (Rattus norvegicus), M-type}
agiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpsfpalpsslgfk
elgpyssktrgiewkrpteicadpqfiiggatrtdicqgalgdswllaaiasltlneeil
arvvpldqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftggiaewyelrkpppnlfkiiqkalekgsllgcs
idighaysvtgaeevqklirirnpwgqgefwmsfsdflrhysrleicnltpdtltcdsyk
k

Timeline for d1df0a3:

• d1df0a3 first appeared (with stable ids) in SCOP 1.55
  
• d1df0a3 appears in SCOP 1.69
  
• d1df0a3 appears in SCOP 1.73
  
• d1df0a3 appears in the current release, SCOPe 2.08