SCOPe 2.08: Domain d6i2pb_: 6i2p B:

Lineage for d6i2pb_ (6i2p B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [343222] (2 PDB entries)

8. Domain d6i2pb_: 6i2p B: [369127]
   Other proteins in same PDB: d6i2pe_
   automated match to d3orta_
   complexed with acp, mg, so4; mutant

Details for d6i2pb_

PDB Entry: 6i2p, 2.37 Å

PDB Description: crystal structure of the mycobacterium tuberculosis pknb kinase domain (l33e mutant) in complex with its substrate gara

PDB Compounds: (B:) serine/threonine-protein kinase pknb

SCOPe Domain Sequences for d6i2pb_:

Sequence, based on SEQRES records:

>d6i2pb_ d.144.1.7 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
ttpshlsdryelgeilgfggmsevhlardlrehrdvavkvlradlardpsfylrfrreaq
naaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviad
acqalnfshqngiihrdvkpanimisatnavkvmdfgiaraiadsgnsvtqtaavigtaq
ylspeqargdsvdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpippsarhe
glsadldavvlkalaknpenryqtaaemradlvrvh

Sequence, based on observed residues (ATOM records):

>d6i2pb_ d.144.1.7 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
ttpshlsdryelgeilgfggmsevhlardlrehrdvavkvlradlardpsfylrfrreaq
naaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviad
acqalnfshqngiihrdvkpanimisatnavkvmdfgiansvtqtaataqylspeqargd
svdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpippsarheglsadldavv
lkalaknpenryqtaaemradlvrvh

Timeline for d6i2pb_:

• d6i2pb_ first appeared in SCOPe 2.07