Lineage for d6md7b3 (6md7 B:219-525)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2454571Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2454572Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2454684Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2454892Protein automated matches [190252] (4 species)
    not a true protein
  7. 2454893Species Human (Homo sapiens) [TaxId:9606] [187034] (44 PDB entries)
  8. 3064818Domain d6md7b3: 6md7 B:219-525 [364880]
    Other proteins in same PDB: d6md7a1, d6md7a2, d6md7b1, d6md7b2
    automated match to d2shpa1
    complexed with je1, po4

Details for d6md7b3

PDB Entry: 6md7 (more details), 1.96 Å

PDB Description: non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrimidinone 7
PDB Compounds: (B:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d6md7b3:

Sequence, based on SEQRES records: (download)

>d6md7b3 c.45.1.2 (B:219-525) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsklaettdkvkqgfweefetlqqqeckllysrkegqrqenknknr
yknilpfdhtrvvlhdgdpnepvsdyinaniimpefetkcnnskpkksyiatqgclqntv
ndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvkesaahdytl
relklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesimdagpvvvh
csagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymav
qhyietl

Sequence, based on observed residues (ATOM records): (download)

>d6md7b3 c.45.1.2 (B:219-525) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelskqgfweefetlqqqeckllysrkegqrqenknknryknilpfdh
trvvlhvsdyinaniimpepkksyiatqgclqntvndfwrmvfqensrvivmttkeverg
kskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrtw
pdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiirekg
vdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietl

SCOPe Domain Coordinates for d6md7b3:

Click to download the PDB-style file with coordinates for d6md7b3.
(The format of our PDB-style files is described here.)

Timeline for d6md7b3:

  • d6md7b3 appears in periodic updates to SCOPe 2.07 starting on 2019-02-14