SCOPe 2.08: Domain d5q0ca_: 5q0c A:

Lineage for d5q0ca_ (5q0c A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.7: Carbohydrate phosphatase [56654] (1 superfamily)
   N-terminal domain is an alpha+beta, C-terminal domain is an alpha/beta with mixed beta-sheet

4. Superfamily e.7.1: Carbohydrate phosphatase [56655] (3 families)

5. Family e.7.1.1: Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (7 proteins)

6. Protein automated matches [190281] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187709] (50 PDB entries)

8. Domain d5q0ca_: 5q0c A: [362457]
   automated match to d1fsaa_
   complexed with 96g, fdp

Details for d5q0ca_

PDB Entry: 5q0c, 2.4 Å

PDB Description: human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, e.c.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2- yl]sulfonylurea and with fructose-2,6-diphosphate

PDB Compounds: (A:) Fructose-1,6-bisphosphatase isozyme 2

SCOPe Domain Sequences for d5q0ca_:

Sequence; same for both SEQRES and ATOM records:

>d5q0ca_ e.7.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tdmltltryvmekgrqakgtgeltqllnsmltaikaissavrkaglahlygiagsvnvtg
devkkldvlsnslvinmlqssystcvlvseenkdaiitakekrgkyvvcfdpldgssnid
clasigtifaiyrktsedepsekdalqcgrnivaagyalygsatlvalstgqgvdlfmld
palgefvlvekdvkikkkgkiyslnegyakyfdaatteyvqkkkfpedgsapygaryvgs
mvadvhrtlvyggiflypanqkspkgklrllyecnpvayiieqagglattgtqpvldvkp
eaihqrvplilgspedvqeyltcvqknq

Timeline for d5q0ca_:

• d5q0ca_ first appeared in SCOPe 2.07