SCOPe 2.07: Domain d6md2b_: 6md2 B:

Lineage for d6md2b_ (6md2 B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (132 PDB entries)
   Uniprot P37231 232-505

8. Domain d6md2b_: 6md2 B: [362198]
   automated match to d2xkwa_
   complexed with acd, gw9

Details for d6md2b_

PDB Entry: 6md2, 2.2 Å

PDB Description: crystal structure of human ppargamma ligand binding domain in complex with gw9662 and arachidonic acid

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d6md2b_:

Sequence, based on SEQRES records:

>d6md2b_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiyk

Sequence, based on observed residues (ATOM records):

>d6md2b_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkdkspfviydmnslmmgedkikfkhit
plkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlas
lmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiavii
lsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvql
lqvikktetpllqeiyk

Timeline for d6md2b_:

• d6md2b_ appears in periodic updates to SCOPe 2.07 starting on 2019-01-17