Lineage for d6fexa_ (6fex A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2546221Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2546222Protein automated matches [190417] (28 species)
    not a true protein
  7. 2546365Species Human (Homo sapiens) [TaxId:9606] [187294] (1049 PDB entries)
  8. 3060552Domain d6fexa_: 6fex A: [360614]
    automated match to d3zosa_
    complexed with cl, d6z, iod, mes

Details for d6fexa_

PDB Entry: 6fex (more details), 1.29 Å

PDB Description: ddr1, 2-[4-bromo-2-oxo-1'-(1h-pyrazolo[4,3-b]pyridine-5-carbonyl) spiro[indole-3,4'-piperidine]-1-yl]-n-(2,2,2-trifluoroethyl) acetamide, 1.291a, p212121, rfree=17.4%
PDB Compounds: (A:) epithelial discoidin domain-containing receptor 1

SCOPe Domain Sequences for d6fexa_:

Sequence, based on SEQRES records: (download)

>d6fexa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrpda
tknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledk
aaegapgdptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgm
srnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgq
ltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflae
d

Sequence, based on observed residues (ATOM records): (download)

>d6fexa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvdfprsrlrfkeklgegqfgevhlcevdspqdlvfplnvrkghpllvavkilrpdatkn
arndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledptis
ypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgmsrnlyagdyyrv
qgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqvienage
ffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaed

SCOPe Domain Coordinates for d6fexa_:

Click to download the PDB-style file with coordinates for d6fexa_.
(The format of our PDB-style files is described here.)

Timeline for d6fexa_:

  • d6fexa_ appears in periodic updates to SCOPe 2.07 starting on 2018-11-29