Lineage for d6msyh1 (6msy H:1-115)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2344608Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2344609Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2344610Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2344816Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2344820Species Engineered (including hybrid species) [88562] (71 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # humanized antibody ! SQ NA # Humanized antibody ! SQ NA # engineered antibody
  8. 3060434Domain d6msyh1: 6msy H:1-115 [360496]
    Other proteins in same PDB: d6msyh2, d6msyl1, d6msyl2
    automated match to d1op3h1
    complexed with act, man, unx

Details for d6msyh1

PDB Entry: 6msy (more details), 2 Å

PDB Description: anti-hiv-1 fab fab 2g12 + man4 re-refinement
PDB Compounds: (H:) FAB 2G12, heavy chain

SCOPe Domain Sequences for d6msyh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d6msyh1 b.1.1.1 (H:1-115) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}
evqlvesggglvkaggslilscgvsnfrisahtmnwvrrvpggglewvasistsstyrdy
adavkgrftvsrddledfvylqmhkmrvedtaiyycarkgsdrlsdndpfdawgpgtvvt
vspas

SCOPe Domain Coordinates for d6msyh1:

Click to download the PDB-style file with coordinates for d6msyh1.
(The format of our PDB-style files is described here.)

Timeline for d6msyh1:

  • d6msyh1 appears in periodic updates to SCOPe 2.07 starting on 2018-11-22

View in 3D
Domains from same chain:
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d6msyh2