Lineage for d6crfb2 (6crf B:219-525)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2454571Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2454572Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2454684Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2454892Protein automated matches [190252] (4 species)
    not a true protein
  7. 2454893Species Human (Homo sapiens) [TaxId:9606] [187034] (38 PDB entries)
  8. 3059724Domain d6crfb2: 6crf B:219-525 [359786]
    Other proteins in same PDB: d6crfa1, d6crfa3, d6crfb1
    automated match to d2shpa1
    complexed with gol; mutant

Details for d6crfb2

PDB Entry: 6crf (more details), 2.62 Å

PDB Description: crystal structure of shp2 e76k gof mutant in the open conformation
PDB Compounds: (B:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d6crfb2:

Sequence, based on SEQRES records: (download)

>d6crfb2 c.45.1.2 (B:219-525) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsklaettdkvkqgfweefetlqqqeckllysrkegqrqenknknr
yknilpfdhtrvvlhdgdpnepvsdyinaniimpefetkcnnskpkksyiatqgclqntv
ndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvkesaahdytl
relklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesimdagpvvvh
csagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymav
qhyietl

Sequence, based on observed residues (ATOM records): (download)

>d6crfb2 c.45.1.2 (B:219-525) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsqgfweefetlqqqeckllysrkegqrqenknknryknilpfdht
rvvlhdgdpnepvsdyinaniimpksyiatqgclqntvndfwrmvfqensrvivmttkev
ergkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhf
rtwpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiir
ekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietl

SCOPe Domain Coordinates for d6crfb2:

Click to download the PDB-style file with coordinates for d6crfb2.
(The format of our PDB-style files is described here.)

Timeline for d6crfb2:

  • d6crfb2 appears in periodic updates to SCOPe 2.07 starting on 2018-11-08