Lineage for d6crga2 (6crg A:111-218)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2530460Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
  4. 2530461Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 2530930Family d.93.1.0: automated matches [191409] (1 protein)
    not a true family
  6. 2530931Protein automated matches [190561] (4 species)
    not a true protein
  7. 2530932Species Human (Homo sapiens) [TaxId:9606] [187549] (63 PDB entries)
  8. 3059716Domain d6crga2: 6crg A:111-218 [359778]
    Other proteins in same PDB: d6crga3, d6crgb3
    automated match to d2shpa3
    complexed with 5od, gol, so4; mutant

Details for d6crga2

PDB Entry: 6crg (more details), 2.75 Å

PDB Description: crystal structure of shp2 e76k gof mutant in complex with shp099
PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d6crga2:

Sequence, based on SEQRES records: (download)

>d6crga2 d.93.1.0 (A:111-218) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rwfhghlsgkeaeklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthv
mircqelkydvgggerfdsltdlvehykknpmvetlgtvlqlkqplnt

Sequence, based on observed residues (ATOM records): (download)

>d6crga2 d.93.1.0 (A:111-218) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rwfhghlsgkeaeklltekgkhgsflvresqshpgdfvlsvrtgsndgkskvthvmircq
elkydvgggerfdsltdlvehykknpmvetlgtvlqlkqplnt

SCOPe Domain Coordinates for d6crga2:

Click to download the PDB-style file with coordinates for d6crga2.
(The format of our PDB-style files is described here.)

Timeline for d6crga2:

  • d6crga2 appears in periodic updates to SCOPe 2.07 starting on 2018-11-08