Lineage for d6gbxc_ (6gbx C:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2464564Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2466053Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 2466496Family c.56.5.8: Glutaminyl-peptide cyclotransferase-like [142532] (1 protein)
    part of Pfam PF04389
  6. 2466497Protein Glutaminyl-peptide cyclotransferase, QPCT [142533] (2 species)
    Glutaminyl cyclase
  7. 2466498Species Human (Homo sapiens) [TaxId:9606] [142534] (23 PDB entries)
    Uniprot Q16769 33-361
  8. 3057728Domain d6gbxc_: 6gbx C: [357790]
    automated match to d3pbea_
    complexed with edo, s77, so4, zn

Details for d6gbxc_

PDB Entry: 6gbx (more details), 1.72 Å

PDB Description: crystal structure of human glutaminyl cyclase variant y115e-y117e in complex with sen177
PDB Compounds: (C:) Glutaminyl-peptide cyclotransferase

SCOPe Domain Sequences for d6gbxc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6gbxc_ c.56.5.8 (C:) Glutaminyl-peptide cyclotransferase, QPCT {Human (Homo sapiens) [TaxId: 9606]}
sawpeeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhimq
riqrlqadwvleidtflsqtpegersfsniistlnptakrhlvlachydskyfshwnnrv
fvgatdsavpcammlelaraldkkllslktvsdskpdlslqliffdgeeaflhwspqdsl
ygsrhlaakmastphppgargtsqlhgmdllvlldligapnptfpnffpnsarwferlqa
iehelhelgllkdhslegryfqnysyggviqddhipflrrgvpvlhlipspfpevwhtmd
dneenldestidnlnkilqvfvleylhl

SCOPe Domain Coordinates for d6gbxc_:

Click to download the PDB-style file with coordinates for d6gbxc_.
(The format of our PDB-style files is described here.)

Timeline for d6gbxc_:

  • d6gbxc_ appears in periodic updates to SCOPe 2.07 starting on 2018-09-20