SCOPe 2.08: Domain d6ae3c_: 6ae3 C:

Lineage for d6ae3c_ (6ae3 C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (2 species)
   CMGC group; GSK3 subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [357651] (1 PDB entry)

8. Domain d6ae3c_: 6ae3 C: [357703]
   automated match to d1j1bb_
   complexed with gol, mri

Details for d6ae3c_

PDB Entry: 6ae3, 2.14 Å

PDB Description: crystal structure of gsk3beta complexed with morin

PDB Compounds: (C:) Glycogen synthase kinase-3 beta

SCOPe Domain Sequences for d6ae3c_:

Sequence, based on SEQRES records:

>d6ae3c_ d.144.1.7 (C:) Glycogen synthase kinase-3 beta (Gsk3b) {Mouse (Mus musculus) [TaxId: 10090]}
vttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfknr
elqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlpvi
yvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsy
icsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtp
treqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleaca
hsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

Sequence, based on observed residues (ATOM records):

>d6ae3c_ d.144.1.7 (C:) Glycogen synthase kinase-3 beta (Gsk3b) {Mouse (Mus musculus) [TaxId: 10090]}
vttvvatpgqpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrknrel
qimrkldhcnivrlryffyskdevylnlvldyvpetvyrvarhysrakqtlpviyvklym
yqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryy
rapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqir
emnqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklp
ngrdtpalfnfttqelssnpplatilipphar

Timeline for d6ae3c_:

• d6ae3c_ first appeared in SCOPe 2.07