Lineage for d5xffa_ (5xff A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2545120Protein automated matches [190091] (17 species)
    not a true protein
  7. 2545220Species Human (Homo sapiens) [TaxId:9606] [188447] (660 PDB entries)
  8. 3057112Domain d5xffa_: 5xff A: [357174]
    automated match to d5am7a_
    complexed with 6lf; mutant

Details for d5xffa_

PDB Entry: 5xff (more details), 2.7 Å

PDB Description: crystal structure of ly2874455 in complex of fgfr4 gatekeeper mutation (v550l)
PDB Compounds: (A:) Fibroblast growth factor receptor 4

SCOPe Domain Sequences for d5xffa_:

Sequence, based on SEQRES records: (download)

>d5xffa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlpldplwefprdrlvlgkplgegafgqvvraeafgmdparpdqastvavkmlkdnasdk
dladlvsemevmkligrhkniinllgvctqegplyvilecaakgnlreflrarrppgpdl
spdgprssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfg
largvhhidyykktsngrlpvkwmapealfdrvythqsdvwsfgillweiftlggspypg
ipveelfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkvllav

Sequence, based on observed residues (ATOM records): (download)

>d5xffa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dlpldplwefprdrlvlgkplgegafgqvvraeafgmdparpdqastvavkmlkdnasdk
dladlvsemevmkligrhkniinllgvctqegplyvilecaakgnlreflrarrppgppl
sfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfgllpvkwmapeal
fdrvythqsdvwsfgillweiftlggspypgipveelfsllreghrmdrpphcppelygl
mrecwhaapsqrptfkqlvealdkvllav

SCOPe Domain Coordinates for d5xffa_:

Click to download the PDB-style file with coordinates for d5xffa_.
(The format of our PDB-style files is described here.)

Timeline for d5xffa_:

  • d5xffa_ appears in periodic updates to SCOPe 2.07 starting on 2018-09-06