SCOPe 2.08: Domain d6c7ic_: 6c7i C:

Lineage for d6c7ic_ (6c7i C:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d6c7ic_: 6c7i C: [356014]
   Other proteins in same PDB: d6c7ia2, d6c7ib2
   automated match to d5vp0b_
   complexed with ep7, mg, zn

Details for d6c7ic_

PDB Entry: 6c7i, 1.71 Å

PDB Description: crystal structure of human phosphodiesterase 2a with 1-(2-chloro-5- methoxy-phenyl)-n-isobutyl-4-methyl-[1,2,4]triazolo[4,3- a]quinoxaline-8-carboxamide

PDB Compounds: (C:) cGMP-dependent 3',5'-cyclic phosphodiesterase

SCOPe Domain Sequences for d6c7ic_:

Sequence, based on SEQRES records:

>d6c7ic_ a.211.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eytkllhdgiqpvaaidsnfasftytprslpeddtsmailsmlqdmnfinnykidcptla
rfclmvkkgyrdppyhnwmhafsvshfcyllyknleltnyledieifalfiscmchdldh
rgtnnsfqvasksvlaalyssegsvmerhhfaqaiailnthgcnifdhfsrkdyqrmldl
mrdiilatdlahhlrifkdlqkmaevgydrnnkqhhrlllcllmtscdlsdqtkgwkttr
kiaeliykeffsqgdlekamgnrpmemmdrekayipelqisfmehiampiykllqdlfpk
aaelyervasnrehwtkvshkftirglpsnnsldfl

Sequence, based on observed residues (ATOM records):

>d6c7ic_ a.211.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eytkllhiqpvaaidsnfasftytprslpeddtsmailsmlqdmnfinnykidcptlarf
clmvkkgyrdppyhnwmhafsvshfcyllyknleltnyledieifalfiscmchdldhrg
tnnsfqvasksvlaalyssegsvmerhhfaqaiailnthgcnifdhfsrkdyqrmldlmr
diilatdlahhlrifkdlqkmaevgydrnnkqhhrlllcllmtscdlsdqtkgwkttrki
aeliykeffsqgdlekamgnrpmemmdrekayipelqisfmehiampiykllqdlfpkaa
elyervasnrehwtkvshkftirglpsnnsldfl

Timeline for d6c7ic_:

• d6c7ic_ first appeared in SCOPe 2.07