SCOPe 2.08: Domain d6aler2: 6ale R:2-3

Lineage for d6aler2 (6ale R:2-3)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (15360 PDB entries)

8. Domain d6aler2: 6ale R:2-3 [355865]
   Other proteins in same PDB: d6aler1
   complexed with 1kp, ca, gol, so4

Details for d6aler2

PDB Entry: 6ale, 2.5 Å

PDB Description: a v-to-f substitution in sk2 channels causes ca2+ hypersensitivity and improves locomotion in a c. elegans als model

PDB Compounds: (R:) Calmodulin-2

SCOPe Domain Sequences for d6aler2:

Sequence; same for both SEQRES and ATOM records:

>d6aler2 l.1.1.1 (R:2-3) N-terminal Tags {Synthetic}
aa

Timeline for d6aler2:

• d6aler2 first appeared in SCOPe 2.07